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THE HISTOCHEMICAL LOCALIZATION OF HISTIDINE IN THE HUMAN EPIDERMIS AND ITS RELATIONSHIP TO ZINC BINDING

EVE P. REAVEN 1 and ALVIN J. CON JR. 1

1 Departments of Dermatology and Pathology, Stanford University School of Medicine, Palo Alto, California

A concentration of histidine in the transitional zone of the human epidermis has been identified by the diazonium coupling reaction. It has been concluded that histidine may be largely responsible for the selective in vitro zinc-binding property of the transitional zone of keratin formation in the epidermis.

Submitted on April 22, 1963


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A. R. Ugel
Keratohyalin: Extraction and in vitro Aggregation
Science, October 10, 1969; 166(3902): 250 - 251.
[Abstract] [PDF]



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