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EFFECT OF ALDEHYDE FIXATION ON CELLULAR RHEUMATOID FACTOR AND CERTAIN TISSUE ANTIGENS

JOHN BALL 1, NOUR EL DIN BAHGAT 1, and GEOFFREY TAYLOR 1

1 Departments of Rheumatism Research and Bacteriology, University of Manchester, Manchester, England

Rheumatoid facor, nuclei, and ggr2 globulins can be identified by immunofluorescence microscopy in alcohol-fixed paraffin-embedded sections, though wax of low melting point is required for preservation of nuclear antigens. Rheumatoid factor also resisted aldehyde fixatives; hence it should be possible to investigate the ultrastructural characteristics of cells containing it.

Submitted on March 4, 1964


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