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ACTIVATION OF GLYCOPROTEIN BIOSYNTHESIS BY TESTESTERONE PROPIONATE ON MOUSE EXORBITAL GLANDS

GIULIANO QUINTARELLI 1 and MARIE C. DELLOVO 1

1 University of Alabama Medical Center, Birmingham, Alabama

The authors have studied the effects of testosterone propionate on the lacrimal gland of the mouse. Repeated injections of the hormone have determined some structural and functional modifications of the gland. The former were characterized by cytoplasmic vacuoles; the latter by an increase of glycoprotein material.

The androgen used seemed to stimulate the synthesis of high molecular weight carbohydrates in a tissue that per se is mainly protein secreting.

Submitted on December 10, 1964


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