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BLOOD GRANULOCYTE STAINING WITH ACRIDINE ORANGE CHANGES WITH INFECTION

M. R. MELAMED 1, F. TRAGANOS 1, L. R. ADAMS 2, and L. A. KAMENTSKY 2

1 Cytology Service, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021
2 Bio/Physics Systems, Inc., Mahopac, New York 10541

Peripheral blood granulocytes from patients with infections take up acridine orange supravitally to produce a greater range of elicitable red cytoplasmic fluorescence per cell than is obtained when infection is absent. It is suggested that this may be another indication of leukocyte mobilization in infection, although the mechanism involved is not yet understood.

Submitted on February 22, 1974


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