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HIGH RESOLUTION SHADING CORRECTION

MORTON L. SCHULTZ 1, LEWIS E. LIPKIN 1, MARTA J. WADE 1, PETER F. LEMKIN 1, and GEORGE M. CARMAN 2

1 Image Processing Unit, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014
2 Carman Electronics, Inc., Corvallis, Oregon 97330

Quantitative cytology requires accurate representation of a specimen's optical densities. As the requirements for measurement precision increase, instrument-induced errors become increasingly more difficult to reduce to the point at which their effect on experimental data is insignificant compared to the measured parameters. Shading induces a significant amount of amplitude ambiguity to data obtained from a scanning system. A method of shading correction on single pixels is introduced as a new way to reduce some errors that currently plague scanning systems.

Submitted on February 4, 1974


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