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AUTOMATED AUTORADIOGRAPHIC GRAIN COUNTING IN HUMAN DETERMINED CONTEXT

LEWIS E. LIPKIN 1, PETER LEMKIN 1, and GEORGE CARMAN 2

1 Image Processing Unit, Division of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20014
2 Carman Electronics, Inc., Corvallis, Oregon 97330

An automated autoradiographic grain counter which dichotomizes results into nuclear and background categories for multiple human determined classes of Romanowsky-stained cells has been constructed. Additional instrument capabilities and functions are indicated as applicable to appropriately prepared material. The operation of the instrument is summarized. Its performance characteristics and its potential role in general quantitative cytology, cytokinetics research and cancer chemotherapy will be evaluated by projected field trial instruments.

Submitted on February 4, 1974


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