|
|
|
|
 |
|||
|
|||
Denervation and reinnervation of fast and slow muscles. A histochemical study in rats
MM Jaweed, GJ Herbison and JF Ditunno
A histochemical study, using myosin-adenosine triphosphatase activity at pH 9.4, was conducted in soleus and plantaris muscles of adult rats, after bilateral crushing of the sciatic nerve at the sciatic notch. The changes in fiber diameter and per cent composition of type I and type II fibers plus muscle weights were evaluated along the course of denervation-reinnervation curve at 1, 2, 3, 4 and 6 weeks postnerve crush. The study revealed that in the early denervation phase (up to 2 weeks postcrush) both the slow and fast muscles, soleus and plantaris, resepctively, atrophied similarly in muscle mass. Soleus increased in the number of type II fibers, which may be attributed to "disuse" effect. During the same period, the type I fibers of soleus atrophied as much or slightly more than the type II fibers; whereas the type II fibers of plantaris atrophied significantly more than the type I fibers, reflecting that the process of denervation, in its early stages, may affect the two fiber types differentially in the slow and fast muscles. It was deduced that the type I fibers of plantaris may be essentially different in the slow (soleus) and fast (plantaris) muscles under study. The onset of reinnervation, as determined by the increase in muscle weight and fiber diameter of the major fiber type, occurred in soleus and plantaris at 2 and 3 weeks postcrush, respectively, which confirms the earlier hypotheses that the slow muscles are reinnervated sooner than the fast muscles. It is suggested that the reinnervation of muscle after crush injury may be specific to the muscle type or its predominant fiber type.
Volume 23,
Issue 11,
pp. 808-827,
11/01/1975
Copyright © 1975 by The Histochemical Society
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  A-J. CARTER, F. KRISTMUNDSDOTTIR, J. GILMOUR, and M. A. GLASBY Changes in Muscle Cytoarchitecture after Peripheral Nerve Injury and Repair: A quantitative and qualitative study J Hand Surg Eur Vol., June 1, 1998; 23(3): 365 - 369. [Abstract] [PDF]
|
|
|
|
 |
|
 G. Zacharová, H. Knotkova-Urbancova, and P. Hnik Nociceptive atrophy of the rat soleus muscle induced by bone fracture: a morphometric study J Appl Physiol, February 1, 1997; 82(2): 552 - 557. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Germinario, A. Esposito, A. Megighian, M. Midrio, D. Biral, R. Betto, and D. Danieli-Betto Early changes of type 2B fibers after denervation of rat EDL skeletal muscle J Appl Physiol, May 1, 2002; 92(5): 2045 - 2052. [Abstract] [Full Text] [PDF]
|
|
| Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact |