Distribution of vitamin B12 R binder in normal human tissues: an immunohistochemical studyH Kudo, G Ohshio, K Ogawa, Y Wakatsuki, M Inada, Y Hamashima and T Miyake
We studied the distribution of vitamin B12 R binder in various normal human tissues by use of an immunoperoxidase technique. Positive staining for R binder was observed in almost all glandular epithelia of digestive system, bronchial glands, renal proximal tubules, prostate, uterus, Fallopian tube, mammary gland, and sweat glands. The distribution of R binder was similar to that of lactoferrin and secretory component. These findings support the hypothesis that R binder plays a role in the local defense mechanism.
Volume 35,
Issue 8,
pp. 855-859,
08/01/1987
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