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Lateral olivocochlear neurons contain both enkephalin and dynorphin immunoreactivities: immunocytochemical co-localization studies

RA Altschuler, KA Reeks, J Fex and DW Hoffman

Kresge Hearing Research Institute, University of Michigan, Ann Arbor 48109-0506.

Antibodies to methionine enkephalin and to dynorphin B were used in an immunocytochemical study examining co-containment of enkephalins and dynorphins in olivocochlear neurons in the guinea pig lateral superior olive. Two methods of sequential co-localization were employed: one using primary antibodies from different species, the second using elution of antibodies. Co-localization of enkephalin-like and dynorphin- like immunoreactivities was found in lateral olivocochlear neurons, suggesting co-containment of enkephalins and dynorphins in this projection pathway from the lateral superior olive to the organ of Corti.

Volume 36, Issue 7, pp. 797-801, 07/01/1988
Copyright © 1988 by The Histochemical Society


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