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Expression of c-myc proto-oncogene in normal human intestinal epithelium

J ten Kate, S Eidelman, FT Bosman and I Damjanov

Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.

We studied the expression of the human c-myc proto-oncogene in normal human colon epithelium by both in situ hybridization and immunohistochemistry. c-myc was found to be expressed uniformly throughout the entire thickness of the colon epithelium. The present findings do not support the contention that the c-myc proto-oncogene is primarily expressed in proliferating intestinal epithelial cell compartments.

Volume 37, Issue 4, pp. 541-545, 04/01/1989
Copyright © 1989 by The Histochemical Society


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The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1989