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Distribution of serotonin-like immunoreactive nerves in major cerebral arteries of rabbit: an immunohistochemical study

U Dhall and G Burnstock

Department of Anatomy and Developmental Biology, University College London, United Kingdom.

We studied the distribution pattern of serotonin-like immunoreactive nerve fibers in the major cerebral vessels of rabbit by an indirect immunofluorescence technique using whole-mount stretch preparations. The density of serotonin-like immunoreactive nerve fibers was greater in vessels of the posterior part of the circle of Willis compared with that in the anterior part. This is in contrast to most of the observations reported previously regarding adrenergic, cholinergic, and peptidergic innervation of the circle of Willis.

Volume 37, Issue 9, pp. 1383-1386, 09/01/1989
Copyright © 1989 by The Histochemical Society


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