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Ultrastructural cytochemistry of the mammalian cell nucleolus

M Derenzini, M Thiry and G Goessens

Dipartimento di Patologia Sperimentale, Universita di Bologna, Italy.

In the present review on the organization of the mammalian cell nucleolus, we report and discuss data obtained during the past 10 years by means of cytochemical and immunocytochemical ultrastructural techniques. Particular emphasis is placed on the following topics: location of the nucleolus organizer regions in interphasic nucleolar components, structure of nucleolar chromatin in situ, and the structure- function relationship of the nucleolar components. The cytochemical and immunocytochemical results are compared and the concordant data are stressed for each topic.

Volume 38, Issue 9, pp. 1237-1256, 09/01/1990
Copyright © 1990 by The Histochemical Society


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