Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Childs, G. V.
Right arrow Articles by Komak, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Childs, G. V.
Right arrow Articles by Komak, S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Histochemistry and Cytochemistry, Vol. 49, 665-666, May 2001, Copyright © 2001, The Histochemical Society, Inc.

BRIEF REPORT

Differential Expression of Estradiol Receptors Alpha and Beta by Gonadotropes During the Estrous Cycle

Gwen V. Childsa,b, Geda Unabiab, and Spogmai Komakb
a Department of Anatomy, University of Arkansas for Medical Science, Little Rock, Arkansas
b Department of Anatomy and Neuroscience, University of Texas Medical Branch, Galveston, Texas

Correspondence to: Gwen V. Childs, Dept. of Anatomy, Univ. of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 510, Little Rock, AR 72205-7199.

This study focused on expression of estradiol receptors (ER) during the estrous cycle. Labeling for ER{alpha} or ß antigens and luteinizing hormone (LH) or follicle-stimulating hormone (FSH) ß-subunits was done on freshly dispersed pituitary cells. The lowest expression of ER{alpha} and ß was seen in estrus (23% and 12%, respectively). Expression increased to 42–54% of pituitary cells by diestrus. In males, cells with ER{alpha} or ß were 37% or 20% of the population, respectively. ER{alpha} or ß and gonadotropin antigens were in 6–9% of pituitary cells from male rats. Early in the cycle (estrus and metestrus), less than 5% of pituitary cells expressed ER{alpha} or ß with gonadotropins. These values doubled to reach a peak of 10% during proestrus (just before ovulation). These data show that a rise in expression of both ER{alpha} and ERß is a part of preovulatory differentiation of pituitary gonadotropes.

(J Histochem Cytochem 49:665–666, 2001)

Key Words: estrous cycle, estrogen receptors, pituitary cells, differentiation


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 EndocrinologyHome page
T. Kitahashi, S. Ogawa, T. Soga, Y. Sakuma, and I. Parhar
Sexual Maturation Modulates Expression of Nuclear Receptor Types in Laser-Captured Single Cells of the Cichlid (Oreochromis niloticus) Pituitary
Endocrinology, December 1, 2007; 148(12): 5822 - 5830.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
G. Galmiche, N. Richard, S. Corvaisier, and M.-L. Kottler
The Expression of Aromatase in Gonadotropes Is Regulated by Estradiol and Gonadotropin-Releasing Hormone in a Manner that Differs from the Regulation of Luteinizing Hormone
Endocrinology, September 1, 2006; 147(9): 4234 - 4244.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
G. V. Childs, M. Iruthayanathan, N. Akhter, G. Unabia, and B. Whitehead-Johnson
Bipotential Effects of Estrogen on Growth Hormone Synthesis and Storage in Vitro
Endocrinology, April 1, 2005; 146(4): 1780 - 1788.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
I. J. Clarke, V. A. Tobin, S. Pompolo, and A. Pereira
Effects of Changing Gonadotropin-Releasing Hormone Pulse Frequency and Estrogen Treatment on Levels of Estradiol Receptor-{alpha} and Induction of Fos and Phosphorylated Cyclic Adenosine Monophosphate Response Element Binding Protein in Pituitary Gonadotropes: Studies in Hypothalamo-Pituitary Disconnected Ewes
Endocrinology, March 1, 2005; 146(3): 1128 - 1137.
[Abstract] [Full Text] [PDF]



Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 2001