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Journal of Histochemistry and Cytochemistry
Volume 51 (12): 1581-1587, 2003
Copyright ©The Histochemical Society, Inc.

Hsp40 Is Involved in Cilia Regeneration in Sea Urchin Embryos

Caterina Casano, Fabrizio Gianguzza, Maria C. Roccheri, Rossana Di Giorgi, Luigia Maenza and Maria A. Ragusa

Dipartimento di Biologia Cellulare e dello Sviluppo ‘Alberto Monroy,’ Palermo, Italy

Correspondence to: Caterina Casano, Dipartimento di Biologia Cellulare e dello Sviluppo ‘Alberto Monroy,’ Viale delle Scienze, Parco d'Orleans, Piazza ‘Alessandro Cestelli,’ 90128 Palermo, Italy. E-mail: cascate{at}unipa.it

In a previous paper we demonstrated that, in Paracentrotus lividus embryos, deciliation represents a specific kind of stress that induces an increase in the levels of an acidic protein of about 40 kD (p40). Here we report that deciliation also induces an increase in Hsp40 chaperone levels and enhancement of its ectodermal localization. We suggest that Hsp40 might play a chaperoning role in cilia regeneration.

(J Histochem Cytochem 51:1581–1587, 2003)

Key Words: Hsp40 • deciliation • sea urchin


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