Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ZACKS, S. I.
Right arrow Articles by BLUMBERG, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ZACKS, S. I.
Right arrow Articles by BLUMBERG, J. M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

THE HISTOCHEMICAL LOCALIZATION OF ACETYLCHOLINESTERASE IN THE FINE STRUCTURE OF NEUROMUSCULAR JUNCTIONS OF MOUSE AND HUMAN INTERCOSTAL MUSCLE

S. I. ZACKS 1 and J. M. BLUMBERG 1

1 Armed Forces Institute of Pathology, Washington, D. C.

The localization of acetylcholinesterase activity in the fine structure of mouse and human neuromuscular junctions was studied by the method of Barrnett and Palade. A formolsucrose solution was used for primary fixation followed by osmification. It was found that deposits of lead sulphide, the product of the histochemical reaction, were found in axonal and sarcoplasmic mitochondria and most prominently in the primary and secondary synaptic clefts of the subneural apparatus.

Rarely were reactive sites found near the M-band. Control experiments utilizing inhibitors and high concentrations of Pb(NO3)2 were performed.

The possible significance of acetylcholinesterase activity in the areas described is discussed.

Submitted on August 16, 1960


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?





Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1961